Syphilis is a chronic infectious disease that is transmitted predominantly through sexual intercourse. There are four periods of the disease: incubation, primary, secondary and tertiary. Typical is only primary syphilis. With secondary and tertiary syphilis, the symptoms of the disease can be varied. In the development of the disease, periods of imaginary recovery are possible.


Symptoms of syphilis depend on the stage of the disease.

Primary stage:

  • A red, painless ulcer at the site of the infectious agent.
  • Enlargement of lymph nodes.

Secondary stage:

  • Rashes on the skin.
  • Inflammation of internal organs.

Tertiary stage:

  • Deep ulcers, scars.
  • Diseases of internal organs.
  • Changes in the psyche.
  • Paralysis.

Primary and secondary syphilis doctors are called early, and tertiary - late.

Primary syphilis

After 3 weeks after infection, a red, painless stain (chancroid) of a rounded shape appears on the site of the pathogen. The appearance of several chancres is possible. Most often they are found on the genitals. They can ulcerate, but they can completely heal. After approximately 2 weeks, nearby lymph nodes increase, and from the eighth week all lymph nodes increase. Some patients may have headaches, joint and muscle pain, insomnia.

Secondary syphilis

On the ninth week of the disease, there is a rash. In the oropharyngeal cavity, the tonsils can form nodules. After a while, the rash disappears. At this stage, internal organs can also be affected (for example, inflammation of the kidneys, inflammation of the membranes of the brain and spinal cord).

Tertiary syphilis

The most commonly affected skin, bones and mucous membranes, as well as internal organs, large vessels, nervous system. In the active stage of the tertiary stage, there are tubercles and large nodes, which, disintegrating, form slowly healing ulcers with the formation of coarse scars. They often affect the mucous membrane and bones of the nose, soft palate, causing destruction of these tissues and deformation after scarring. Syphilitic lesions of the spinal cord and brain can lead to the development of dorsal and progressive paralysis. The manifestations of the tertiary stage are particularly severe, lead to disfigurement, disability and death. Over time, there is a degradation of personality. The disease is slowly progressing and after many years the patient dies.

Not every change in the skin in the genital area is a symptom of a venereal disease. However, in any case it is necessary to consult a doctor, since The reason for the occurrence of changes can only be established by a specialist.

Causes of the disease

The causative agent of syphilis is pale treponema. In 80-90% of cases, infection occurs sexually, but infection is possible through household items and blood transfusions. Another way is intrauterine infection from a sick mother through the placenta.


Primary and secondary syphilis is successfully treated with antibiotics (penicillin, bicillin-3, bicillin-5, erythromycin). At the tertiary stage, complete recovery is impossible.

It is necessary to avoid accidental sexual intercourse and use a condom.

At the slightest suspicion of this infectious disease, you should immediately consult a doctor. This should be done in all cases of sexually transmitted diseases.

The doctor will conduct a study of serous fluid taken from the affected area on the skin. The blood test gives a positive result 4-6 weeks after infection.


1. Brucellosis of cow type
2. Venereal lymphogranuloma
3. Cutaneous and visceral leishmaniasis
4. Viral infections
5. Diseases