Kidney Diseases

Amyloidosis: Symptoms, Treatments, Prognosis, Causes

Amyloidosis is a disease in which a special substance - amyloid - is formed and deposited in various organs, including kidneys. Amyloid is a complex protein - a glucoprotein. It consists of 75 different amino acids, a small amount of carbohydrates, lipids and other substances. Amino acid composition of amyloid differs from the composition of tissue and serum proteins. Amyloid includes thin fibers, fibrils, and an unstructured mass. In the parenchymal organs, it is deposited mainly peri-reticularly, in other cases - pericollagenic. Amyloid is firmly bound to tissue elements and is resistant to the action of enzymes. Amyloidosis of the kidney is observed in 1-2% of nephrologic patients,...

Glomerulonephritis: Causes, Symptoms, and Treatment

What is glomerulonephritis? Glomerulonephritis is a kidney disease affecting the renal glomeruli. Kidneys consist of millions of microscopic filters called renal glomeruli. The glomeruli recognize the release products to be removed, for example urea. Renal glomeruli act as microscopic filters: together with water, single molecules of salts or harmful substances are removed from the blood. Usually glomerulonephritis is a consequence of other diseases, but sometimes it can start spontaneously (for no apparent reason). Symptoms of glomerulonephritis Fatigue, exhaustion. High blood pressure. Oliguria, nausea. Dark urine. Headaches and kidney pain. Visual disturbances....

Interstitial Nephritis: Causes, Symptoms & Diagnosis

Chronic interstitial nephritis is a kidney disease caused by analgesics. Other names of this disease are analgesic nephropathy and a kidney afflicted with phenacetin. Interstitial nephritis is a non-bacterial inflammation of the interstitial (interstitial) tissue of the kidneys. Unlike pyelonephritis, there is no destruction (destruction) of connective tissue caused by local action of microbes in this disease. Interstitial nephritis occurs most often after taking various medications (antibiotics, sulfonamides), after vaccination, infection and some other conditions. Symptoms of interstitial nephritis Headache. Depression. Decreased efficiency. Slight grayish complexion. Cyanosis....

Acute Kidney Failure: Causes, Risk Factors & Symptoms

What is acute renal failure? The human kidney secrete about 1500 ml of urine during the day, which is excreted through the urinary tract. The substances in the urine can be removed from the body only in this way. Urea is the final product of protein metabolism; Uric acid is the final product of purine metabolism; Creatinine is one of the natural metabolites formed in muscles from creatine and creatine phosphate. If, due to various reasons, there is a violation of urine output, the nitrogen-containing substances that are formed are not eliminated from the body. If this disorder occurs suddenly, it is called acute renal failure. Symptoms of acute renal failure A strong decrease in...

Polycystic Kidney Disease (PKD) Symptoms, Treatments, & Causes

Polycystic kidney disease is a congenital disease characterized by the formation and growth of cysts in both kidneys. Polycystic kidney disease is a congenital anomaly of their development. This is the most frequent developmental defect, it is often combined with polycystosis of other organs (liver, pancreas, lungs, etc.). The disease is often of a family nature. As a rule, both kidneys are involved in the process. Cysts are formed at the stage of the secondary kidney as a result of the absence or incorrect attachment of the secretory and excretory elements of the nephron. This leads to a violation of patency for primary urine, increased pressure in the tubules of the kidneys and the...